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原丽红(1979.8-),博士,副研究员,硕士生导师。2008年毕业于中国科学院动物研究所,获生物化学与分子生物学博士学位,同年被引进到广东省昆虫研究所暨华南濒危动物研究所,主要从事功能基因进化、种群遗传及野生动物携带病原体分子流行病学的研究工作。曾先后到英国伦敦大学和布里斯托尔大学从事合作研究。目前主持及参与广东省自然科学基金、广州市珠江科技新星、广东省科学院优秀青年科技人才基金、国际合作项目、国家自然科学基金和广东省科技计划项目等9项;以第一发明人获得授权国家发明专利3项;培养硕士研究生4名,已毕业3名;在 PloS ONE, General and Comparative Endocrinology,Molecular Biology and Evolution,Comparative Biochemistry and Physiology 等国内外学术刊物上发表科研论文30余篇,其中SCI论文11篇。
近5年发表文章目录(*:通讯作者):
1. Lihong Yuan, Xudong Zhao, Benfu Lin, Stephen J. Rossiter, Lingjiang He, Xueguo Zuo, Guimei He, Gareth Jones, Fritz Geiser, Shuyi Zhang*. Adaptive evolution of Leptin in heterothermy bats. PLoS ONE, 2011, 6(11): e27189.
2. Benfu Lin, Lihong Yuan*, Jinping Chen. Selection pressure drives the co-evolution of several lipid metabolism genes in mammals. Chinese Science Bulletin, 2011, in press.
3. Lihong Yuan, Jianjun Xia, Lvping Zhang, Chaoqun Hu*. Development of 16 microsatellite loci of the tropical sea cucumber Stichopus horrens with cross-amplification in the congeneric species Stichopus monotuberculatus. Conservation Genetic Resources, 2011, published online (DOI 10.1007/s12686-011-9530-4).
4. Lingjiang He, Yihsuan Pan, Guimei He, Benfu Lin, Chen-Chung Liao, Xueguo Zuo, Lihong Yuan*. Structural and functional studies of leptins from hibernating and non-hibernating bats. General and Comparative Endocrinology, 2010, 168: 29-35.
5. Lihong Yuan, Xueguo Zuo, Lingjiang He, Paul Racey, Shuyi Zhang. Cloning and characterization of novel isoforms of the BOULE gene in bats. Biochemical Genetics, 2010, 48: 173-180.
6. Zhe Wang, Lihong Yuan, Stephen J. Rossiter, et al. Adaptive evolution of 5’HoxD genes in the origin and diversification of the cetacean flipper. Molecular Biology and Evolution, 2009 26(3):613-622.
7. Zhe Wang#, Lihong Yuan#, Xueguo Zuo, et al., Variations in the sequences of BMP2 imply different mechanisms for the evolution of morphological diversity in vertebrates. Comparative Biochemistry and Physiology-Part D, 2009, 4, 100-104. (# contributed equally)
8. Lihong Yuan, Xueguo Zuo, Jinping Chen, Benfu Lin, Junpeng Zhang, Min Sun, Shuyi Zhang. Differential expression analysis of Liprin-α2 in hibernating bat (Rhinolophus ferrumequinum). Progress in Nature Science, 2008, 18, 27-32.
9. Lihong Yuan, Jinping Chen, Benfu Lin, Junpeng Zhang, Shuyi Zhang. Differential expression and functional constraint of PRL-2 in hibernating bat. Comparative Biochemistry and Physiology-Part B, 2007, 148, 375-381.
10. Lihong Yuan, Jinping Chen, Benfu Lin, Bing Liang, Shyi Zhang, Donghai Wu. Up-regulation of a non-kinase activity isoform of Ca2+ /calmodulin-dependent protein kinase kinase beta1 (CaMKKβ1) in hibernating bat. Comparative Biochemistry and Physiology-Part B, 2007, 146, 438–444.
11. Jinping Chen, Lihong Yuan, Min Sun, Libiao Zhang, Shuyi Zhang. Screening of hibernation-related genes in the brain of Rhinolophus ferrumequinum during hibernation. Comparative Biochemistry and Physiology-Part B, 2008, 149, 388-393.
12. 何灵江,原丽红*. 人类溶酶体与溶酶体疾病. 生物学教学. 2010, 35: 2-4.
13. 左学国,何灵江,张俊鹏,原丽红*. 三种蝙蝠解偶连蛋白2(UCP2)基因的克隆及进化分析[J]. 华东师范大学学报,2009,(6):38-46.
14. 原丽红,林本夫. 转基因小鼠在现代生命科学中的应用[J]. 生物技术通报, 2009, 67-70.
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